FrameDP est un outil de prédiction de gènes particulièrement ciblé sur l'analyse de transcrits eucaryotes maturés reconstruits à partir d'ESTs ou de lectures de type RNASeq. Il permet en particulier de corriger les décalages de phase et de traiter des séquences d'origines hétérogènes (contamination, symbiotes...).
Transcriptome sequencing represents a fundamental source of information for genome-wide studies and transcriptome analysis and will become increasingly important for expression analysis as new sequencing technologies takes over array technology. The identification of the protein-coding region in
transcript sequences is a prerequisite for systematic amino acid-level analysis and more specifically for domain identification. In this article, we present FrameDP, a self-training integrative pipeline for predicting CDS in transcripts which can adapt itself to different levels of sequence qualities
Langage Perl